1983, 6x9, 270 pp., cloth, $28.50, ISBN: 0-910286-89-2

CIRCADIAN rhythms appear in some symptoms of depression such as early morning awakening and diurnal mood variation. Do abnormalities in the timing of biological rhythms result in depression? Topics examined: body temperature and depression; around-the-clock studies; the importance of lithium; 48-hour cycles; seasonal variation in mood; light as therapy and the hormone melatonin; the switch from mania to depression; pineal gland function; antidepressant drugs and rhythms; phase advance as treatment.